Mechanism of action of Fentanyl

Mechanism of action of Fentanyl
Acts at specific opioid receptors, causing analgesia, respiratory depression, physical depression, euphoria.

Indications of Fentanyl

1. Analgesic action of short duration during anesthesia and in the immediate
   postoperative period
2. Analgesic supplement in general or regional anesthesia
3. Administration with a neuroleptic as an anesthetic premedication, for
   induction of anesthesia, and as an adjunct in maintenance of general and
   regional anesthesia
4. For use as an anesthetic agent with oxygen in selected high-risk patients
5. Transdermal system: management of chronic pain in patients requiring
   opioid analgesia

Contraindications of Fentanyl

1. Contraindicated in the presence of hypersensitivity to narcotics,
   Dhiare caused by poisoning, acute bronchial asthma, upper airway
   obstruction, pregnancy.
2. Use caution in the presence of bradycardia, history of seizures,
   lactation.